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Formulations using cyanocobalamin instead of methylcobalamin require hepatic conversion before B12 becomes active, reducing bioavailability in some patients

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In December 2021, Emergency Use Authorization (EUA) of Paxlovid by the FDA for the treatment of SARS-CoV-2 in mild-to-moderate adults and pediatric and adult patients 12 years of age with a body mass of 40 kg, and in patient populations at higher risk of severe disease